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ORIGINAL ARTICLE
Year : 2019  |  Volume : 1  |  Issue : 1  |  Page : 2-7

Gender difference of blood pressure variables on ambulatory blood pressure monitoring following percutaneous transluminal coronary angioplasty and 1-year outcomes


1 Department of Cardiology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India
2 Consultant Cardiologist, Medicover Hospitals Secretariat (Formerly MaxCure Hospitals) Sarovar Complex, Saifabad, Khairtabad, Secunderabad, Telangana, India

Correspondence Address:
Dr. Maddury Jyotsna
Department of Cardiology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ACCJ.ACCJ_6_19

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Background and Aim: Lack of fall in nocturnal blood pressure (BP) is an independent predictor of poor prognosis. This study determined the prognostic value of BP variables by 24-h ambulatory BP monitoring (ABPM) and associated gender differences after percutaneous transluminal coronary angioplasty (PTCA). Methods: A total of 58 patients underwent PTCA who were subjected to 24-h ABPM and followed for 1-year. Results: All demographic and clinical parameters (female: 10; mean age: 59.4 years), including ABP parameters, were comparable between genders, except smoking and alcoholism. Among nondippers (n = 33), 8 (24.2%) were females, 25 (75.8%) males, 30 (90.9%) diabetes mellitus (DM), 32 (97.0%) hypertension, and had mean diastolic BP (DBP): 86.15 ± 6.31 mmHg, pulse pressure (PP): 55.85 ± 10.09 mmHg, and pulse-wave velocity (PWV): 6.21 ± 01.87 m/s. Most females were nondippers (8 [24.2%]). Nondippers were older in age (P < 0.02) with higher PP (P < 0.001), DBP, and mean BP (MBP). Ejection fraction, presence of coronary artery disease (CAD) or DM, and PWV were comparable between both groups. At 1-year follow-up, one out of two symptomatic patients died, and the other developed chronic stable angina. The major adverse cardiac event rate was 1.7% (1/58). Each left ventricular dysfunction was deteriorated, and contrast-induced nephropathy was seen in three patients. Conclusion: Immediately after PTCA, females were more nondippers than males. Overall, nondippers had higher DBP, MBP, and PP. Nocturnal dipping was not influenced by the presence of DM or CAD. At 1-year follow-up, combined clinical and laboratory events were comparable.


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